CHST8 Antibody

• Background:

  Sulfate groups in carbohydrates confer highly specific functions on glycoproteins, glycolipids, and proteoglycans and are critical for cell-cell interaction, signal transduction, and embryonic development. Sulfotransferases, such as CHST8, carry out sulfation of carbohydrates (Hiraoka et al., 2001 [PubMed 11445554]) .

• NCBI Gene ID:

  64377

• Swiss Prot:

  Q9H2A9

• Accession Number:

  Q9H2A9

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CHST8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-247 amino acids from the Central region of human CHST8.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  49 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CHST8

• NCBI Official Name:

  Carbohydrate sulfotransferase 8

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Melen, E., et al. J. Allergy Clin. Immunol. 126 (3) :631-637 (2010)

• Background Reference 02:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 03:

  Thorleifsson, G., et al. Nat. Genet. 41 (1) :18-24 (2009)

• Background Reference 04:

  Boregowda, R.K., et al. Glycobiology 15 (12) :1349-1358 (2005)

• Other Product Names:

  Carbohydrate sulfotransferase 8, 282-, GalNAc-4-O-sulfotransferase 1, GalNAc-4-ST1, GalNAc4ST-1, N-acetylgalactosamine-4-O-sulfotransferase 1, CHST8

• Tested Applications:

  WB

• Protein ID:

  61212124

• Physical Properties:

  Liquid