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G2E3 Antibody

CAT: 0223-60-196Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-196Size:400 µL
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Background
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death.
NCBI Gene ID
55632
Swiss Prot
Q7L622
Accession Number
Q7L622
Host
Rabbit
Reactivity
Human
Immunogen
This G2E3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-252 amino acids from the Central region of human G2E3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
81 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
G2E3
NCBI Official Name
G2/M phase-specific E3 ubiquitin-protein ligase
NCBI Organism
Homo sapiens
Background Reference 01
Brooks, W.S., et al. J. Biol. Chem. 283 (32) :22304-22315 (2008)
Background Reference 02
Brooks, W.S., et al. Exp. Cell Res. 313 (4) :665-676 (2007)
Background Reference 03
Lehner, B., et al. Genomics 83 (1) :153-167 (2004)
Background Reference 04
Crawford, D.F., et al. J. Biol. Chem. 276 (40) :37166-37177 (2001)
Other Product Names
G2/M phase-specific E3 ubiquitin-protein ligase, 632-, G2E3, KIAA1333
Tested Applications
WB
Protein ID
74738611
Physical Properties
Liquid