SCRIB Antibody

• Background:

  SCRIB is a cytoplasmic multimodular scaffold protein targeted to epithelial adherens junctions and neuronal presynaptic compartments. SCRIB and its orthologs in vertebrates and invertebrates participate in cell polarization (summary by Nola et al., 2008 [PubMed 18716323]) .

• NCBI Gene ID:

  23513

• Swiss Prot:

  Q14160

• Accession Number:

  Q14160

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SCRIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 382-410 amino acids from the N-terminal region of human SCRIB.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  175 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SCRIB

• NCBI Official Name:

  Protein scribble homolog

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Liu, H., et al. J. Virol. 84 (21) :11164-11174 (2010)

• Background Reference 02:

  Nagasaka, K., et al. Oncogene 29 (38) :5311-5321 (2010)

• Background Reference 03:

  Ivanov, A.I., et al. Am. J. Pathol. 176 (1) :134-145 (2010)

• Background Reference 04:

  Ouyang, Z., et al. Oncol. Res. 18 (11-12), 593-599 (2010) :

• Other Product Names:

  Protein scribble homolog, Scribble, hScrib, Protein LAP4, SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL

• Tested Applications:

  WB

• Protein ID:

  261260101

• Physical Properties:

  Liquid