RegisterLogin

SCRIB Antibody / SCRIBBLE

CAT: 0800-RQ4322Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-RQ4322Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
SCRIB, also known as Scribble, SCRIBL, or Scribbled homolog (Drosophila), is a scaffold protein which in humans is encoded by the SCRIB gene. In Drosophila melanogaster, SCRIB is involved in synaptic function, neuroblast differentiation, and epithelial polarization. Mechanistically, the human homolog is a scaffold protein linked to cellular differentiation centered on the regulation of epithelial as well as neuronal morphogenesis. Deficiency in SCRIB impairs many aspects of cell polarity and cell movement. SCRIB is also likely involved in establishing apical-basal polarity as well as progression from the G1 phase to S phase in the cell cycle as a result of its relationship with cell proliferation and exocytosis.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, FACS: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL, Immunofluorescence: 2-4 µg/mL
UniProt
Q14160
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant human protein corresponding to amino acids F172-K409 was used as the immunogen for the SCRIB antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS, IF/ICC, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Reconstitution
After reconstitution, the SCRIB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This SCRIB antibody is available for research use only.
Storage Conditions
After reconstitution, the SCRIB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the SCRIB antibody should be determined by the researcher.
Location
Cell membrane
Image Legend
Western blot testing of human 1) MCF7, 2) COLO-320, 3) 22RV1 and 4) SGC-7901 lysate with SCRIB antibody at 0.5ug/ml. Predicted molecular weight ~175 kDa, routinely observed at 200-240 kDa.

Related Products

CatalogName
RQ4624NONO Antibody / p54nrb Antibody
F53954-0.05MLAntibody
F53954-0.2MLAntibody
F53952-0.05MLAntibody
F53952-0.2MLAntibody
V8674-20UGInhibin alpha Antibody / INHA antibody
V8674SAF-100UGInhibin alpha Antibody / INHA antibody
V8674-100UGInhibin alpha Antibody / INHA antibody
R20161SAF-250UGLambda Light Chain Antibody / Lambda Antibody
R20179SAF-250UGLambda Light Chain Antibody / Lambda Antibody

Alternative Products

CatalogName
abx433587Scribble (SCRIB) Antibody
STJ73632Anti-SCRIB / Scribble antibody
abx218464-01Protein Scribble Homolog (SCRIB) Antibody
TA381304SCRIBBLE (SCRIB) Rabbit Polyclonal Antibody
MBS423847-01Goat Anti-SCRIB/Scribble Antibody
abx615920Scribble (SCRIB) Peptide
TS420211P5SCRIBBLE (SCRIB) CytoSection
SC307489SCRIBBLE (SCRIB) (NM_182706) Human Untagged Clone
SC304298SCRIBBLE (SCRIB) (NM_015356) Human Untagged Clone
GA108357Human SCRIBBLE (SCRIB) activation kit by CRISPRa

Popular Products