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NPY1R Antibody

CAT: 0223-60-137Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-137Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Neuropeptide Y (NPY; MIM 162640) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. Two major subtypes of NPY (Y1 and Y2) have been defined by pharmacologic criteria. NPY receptors, such as NPY1R, have been identified in a variety of tissues, including brain, spleen, small intestine, kidney, testis, placenta, and aortic smooth muscle (Herzog et al., 1992 [PubMed 1321422]) .
NCBI Gene ID
4886
Swiss Prot
P25929
Accession Number
P25929
Host
Rabbit
Reactivity
Human
Immunogen
This NPY1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the Central region of human NPY1R.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Pig
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NPY1R
NCBI Official Name
Neuropeptide Y receptor type 1
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Kim, H.Y., et al. BMB Rep 43 (8) :547-553 (2010)
Background Reference 03
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Background Reference 04
Naukkarinen, J., et al. PLoS Genet. (6), E1000976 (2010) :
Other Product Names
Neuropeptide Y receptor type 1, NPY1-R, NPY1R, NPYR, NPYY1
Tested Applications
WB
Protein ID
128997
Physical Properties
Liquid

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