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MMS19 Antibody

CAT: 0223-60-132Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-132Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MMS19 may play a role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription by interacting with ERCC2/XPD and ERCC3/XPB helicases, both subunits of NER-transcription factor TFIIH. May also function as a transcriptional coactivator of estrogen receptor (ER) . May be involved in regulation of ER activity by bridging TFIIH with ER or may facilitate TFIIH-mediated phosphorylation of ER in specific promoters and cell types.
NCBI Gene ID
64210
Swiss Prot
Q96T76
Accession Number
Q96T76
Host
Rabbit
Reactivity
Human
Immunogen
This MMS19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 411-437 amino acids from the Central region of human MMS19.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
113 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MMS19
NCBI Official Name
MMS19 nucleotide excision repair protein homolog
NCBI Organism
Homo sapiens
Background Reference 01
Ito, S., et al. Mol. Cell 39 (4) :632-640 (2010)
Background Reference 02
Briggs, F.B., et al. Am. J. Epidemiol. 172 (2) :217-224 (2010)
Background Reference 03
McWilliams, R.R., et al. Cancer Epidemiol. Biomarkers Prev. 18 (4) :1295-1302 (2009)
Background Reference 04
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Other Product Names
MMS19 nucleotide excision repair protein homolog, hMMS19, MET18 homolog, MMS19-like protein, MMS19, MMS19L
Tested Applications
WB
Protein ID
150421597
Physical Properties
Liquid

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