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KIT Antibody

CAT: 0223-60-072Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-072Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This is the receptor for stem cell factor (mast cell growth factor) . It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K) .
NCBI Gene ID
3815
Swiss Prot
P10721
Accession Number
P10721
Host
Rabbit
Reactivity
Human
Immunogen
This KIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 556-585 amino acids from the Central region of human KIT.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Pig
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
110 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KIT
NCBI Official Name
Mast/stem cell growth factor receptor Kit
NCBI Organism
Homo sapiens
Background Reference 01
Molderings, G.J., et al. Immunogenetics 62 (11-12), 721-727 (2010) :
Background Reference 02
Cheng, M., et al. Circ. Res. 107 (9) :1083-1093 (2010)
Background Reference 03
Chi, P., et al. Nature 467 (7317) :849-853 (2010)
Background Reference 04
Rossi, S., et al. Am. J. Surg. Pathol. 34 (10) :1480-1491 (2010)
Other Product Names
Mast/stem cell growth factor receptor Kit, SCFR, Piebald trait protein, PBT, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, CD117, KIT, SCFR
Tested Applications
WB
Protein ID
125472
Physical Properties
Liquid

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