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C kit (Ab 936) Antibody

CAT: 0223-79-430Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-430Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This is the receptor for stem cell factor (mast cell growth factor) . It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)
NCBI Gene ID
3815
Swiss Prot
P10721
Accession Number
NP_000213.1
Host
Rabbit
Reactivity
Human
Immunogen
C-kit (Ab-936) antibody was raised against a peptide sequence around aa.934~938 (H-I-Y-S-N) derived from Human c-Kit.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
145 kDa
Specificity
This antibody detects endogenous level of total c-Kit protein.
Applications Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Symbol
KIT
NCBI Official Name
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
NCBI Organism
Homo sapiens
Background Reference 01
Martin, F. H. et al. (1990) Cell 63, 203-11. Blume-Jensen, P. et al. (2000) Nat Genet 24, 157-62. Gommerman, J. L. et al. (1997) J Biol Chem 272, 30519-25. Nocka, K. et al. (1990) EMBO J 9, 1805-13.
Other Product Names
PBT, SCFR, C-Kit, CD117, HSP27, HSP28, KIT, PBT
Tested Applications
WB, IHC
Protein ID
4557695
Physical Properties
Liquid

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