RNF111 Antibody

• Background :

  The protein encoded by this gene contains a RING finger domain, a motif known to be involved in protein-protein and protein-DNA interactions. The mouse counterpart of this gene (Rnf111/arkadia) has been shown to genetically interact with the transforming growth factor (TGF) beta-like factor Nodal, and act as a modulator of the nodal signaling cascade, which is essential for the induction of mesoderm during embryonic development. [provided by RefSeq].

• NCBI Gene ID :

  54778

• Swiss Prot :

  Q6ZNA4

• Accession Number :

  Q6ZNA4

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This RNF111 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-237 amino acids from the N-terminal region of human RNF111.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  109 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  RNF111

• NCBI Official Name :

  E3 ubiquitin-protein ligase Arkadia

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Nagano, Y., et al. J. Biochem. 147 (4) :545-554 (2010)

• Background Reference 02 :

  Cunnington, R.H., et al. Can. J. Physiol. Pharmacol. 87 (10) :764-772 (2009)

• Background Reference 03 :

  Markson, G., et al. Genome Res. 19 (10) :1905-1911 (2009)

• Background Reference 04 :

  Van Wijk, S.J., et al. Mol. Syst. Biol. 5, 295 (2009) :

• Other Product Names :

  E3 ubiquitin-protein ligase Arkadia, 632-, RING finger protein 111, RNF111

• Tested Applications :

  WB

• Protein ID :

  308153555

• Physical Properties :

  Liquid