RNF111 Antibody

• Background:

  The protein encoded by this gene contains a RING finger domain, a motif known to be involved in protein-protein and protein-DNA interactions. The mouse counterpart of this gene (Rnf111/arkadia) has been shown to genetically interact with the transforming growth factor (TGF) beta-like factor Nodal, and act as a modulator of the nodal signaling cascade, which is essential for the induction of mesoderm during embryonic development. [provided by RefSeq].

• NCBI Gene ID:

  54778

• Swiss Prot:

  Q6ZNA4

• Accession Number:

  Q6ZNA4

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RNF111 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-237 amino acids from the N-terminal region of human RNF111.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  109 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RNF111

• NCBI Official Name:

  E3 ubiquitin-protein ligase Arkadia

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Nagano, Y., et al. J. Biochem. 147 (4) :545-554 (2010)

• Background Reference 02:

  Cunnington, R.H., et al. Can. J. Physiol. Pharmacol. 87 (10) :764-772 (2009)

• Background Reference 03:

  Markson, G., et al. Genome Res. 19 (10) :1905-1911 (2009)

• Background Reference 04:

  Van Wijk, S.J., et al. Mol. Syst. Biol. 5, 295 (2009) :

• Other Product Names:

  E3 ubiquitin-protein ligase Arkadia, 632-, RING finger protein 111, RNF111

• Tested Applications:

  WB

• Protein ID:

  308153555

• Physical Properties:

  Liquid