RNF135 Antibody

• Background:

  The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq].

• NCBI Gene ID:

  84282

• Swiss Prot:

  Q8IUD6

• Accession Number:

  Q8IUD6

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RNF135 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 375-401 amino acids from the C-terminal region of human RNF135.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  48 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:500

• Symbol:

  RNF135

• NCBI Official Name:

  E3 ubiquitin-protein ligase RNF135

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :

• Background Reference 02:

  You, F., et al. Nat. Immunol. 10 (12) :1300-1308 (2009)

• Background Reference 03:

  Visser, R., et al. Am. J. Med. Genet.149A (4), 806-808 (2009) :

• Background Reference 04:

  Oshiumi, H., et al. J. Biol. Chem. 284 (2) :807-817 (2009)

• Other Product Names:

  E3 ubiquitin-protein ligase RNF135, 632-, RIG-I E3 ubiquitin ligase, REUL, RING finger protein 135, Riplet, RNF135

• Tested Applications:

  WB

• Protein ID:

  269849639

• Physical Properties:

  Liquid