RNF135 Antibody

• Background :

  The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq].

• NCBI Gene ID :

  84282

• Swiss Prot :

  Q8IUD6

• Accession Number :

  Q8IUD6

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This RNF135 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 375-401 amino acids from the C-terminal region of human RNF135.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  48 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:500

• Symbol :

  RNF135

• NCBI Official Name :

  E3 ubiquitin-protein ligase RNF135

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :

• Background Reference 02 :

  You, F., et al. Nat. Immunol. 10 (12) :1300-1308 (2009)

• Background Reference 03 :

  Visser, R., et al. Am. J. Med. Genet.149A (4), 806-808 (2009) :

• Background Reference 04 :

  Oshiumi, H., et al. J. Biol. Chem. 284 (2) :807-817 (2009)

• Other Product Names :

  E3 ubiquitin-protein ligase RNF135, 632-, RIG-I E3 ubiquitin ligase, REUL, RING finger protein 135, Riplet, RNF135

• Tested Applications :

  WB

• Protein ID :

  269849639

• Physical Properties :

  Liquid