RNF11 Antibody

• Background:

  The protein encoded by this gene contains a RING-H2 finger motif, which is known to be important for protein-protein interactions. The expression of this gene has been shown to be induced by mutant RET proteins (MEN2A/MEN2B) . The germline mutations in RET gene are known to be responsible for the development of multiple endocrine neoplasia (MEN) . [provided by RefSeq].

• NCBI Gene ID:

  26994

• Swiss Prot:

  Q9Y3C5

• Accession Number:

  Q9Y3C5

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RNF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-90 amino acids from the Central region of human RNF11.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  17 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  RNF11

• NCBI Official Name:

  RING finger protein 11

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Santonico, E., et al. Oncogene 29 (41) :5604-5618 (2010)

• Background Reference 02:

  Markson, G., et al. Genome Res. 19 (10) :1905-1911 (2009)

• Background Reference 03:

  Shembade, N., et al. EMBO J. 28 (5) :513-522 (2009)

• Background Reference 04:

  Van Wijk, S.J., et al. Mol. Syst. Biol. 5, 295 (2009) :

• Other Product Names:

  RING finger protein 11, RNF11

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  21362884

• Physical Properties:

  Liquid