RNF121 Antibody

• Background :

  RNF121 is an evolutionarily conserved E3 ligase ring finger protein that is expressed in the endoplasmic reticulum (1) . It acts downstream of the unfolded protein response regulator protein kinase-like endoplasmic reticulum kinase (PERK) . Overexpression of RNF121 during the early stages of gonad development led to aberrations in germline development and gonad migration, suggesting that it plays a role in endoplasmic reticulum-associated degradation machinery (1) .

• NCBI Gene ID :

  552978

• Swiss Prot :

  Q9H920

• Accession Number :

  NP_060790

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Stem Cell

• Purification :

  RNF121 antibody is affinity chromatography purified via peptide column.

• Positive Control :

  Cat. No. 1219 - MCF7 Cell Lysate

• Concentration :

  1 mg/mL

• Buffer :

  RNF121 antibody is supplied in PBS containing 0.02% sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  RNF121 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

• Fragment :

  IgG

• Specificity :

  RNF121 antibody is human, mouse and rat reactive. Multiple isoforms of RNF121 are known to exist.

• Symbol :

  RNF121

• Positive Control 2 :

  Cat. No. 17-012 - MCF7 Cell Slide

• NCBI Official Name :

  Ring finger protein 121

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Darom A, Bening-Abu-Shach U, and Broday L. RNF-121 is an endoplasmic reticulum-membrane E3 ubiquitin ligase involved in the regulation of B-integrin. Mol. Biol. Cell 2010; 21:1788-98.

• Other Product Names :

  Ring finger protein 121

• Tested Applications :

  ELISA, WB, ICC

• Protein ID :

  21361732

• Physical Properties :

  Liquid