RNF121 Antibody

CAT: 0223-8285-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-8285-01Size:0.02 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RNF121 is an evolutionarily conserved E3 ligase ring finger protein that is expressed in the endoplasmic reticulum (1) . It acts downstream of the unfolded protein response regulator protein kinase-like endoplasmic reticulum kinase (PERK) . Overexpression of RNF121 during the early stages of gonad development led to aberrations in germline development and gonad migration, suggesting that it plays a role in endoplasmic reticulum-associated degradation machinery (1) .
NCBI Gene ID
552978
Swiss Prot
Q9H920
Accession Number
NP_060790
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
RNF121 antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1219 - MCF7 Cell Lysate
Concentration
1 mg/mL
Buffer
RNF121 antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
RNF121 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
RNF121 antibody is human, mouse and rat reactive. Multiple isoforms of RNF121 are known to exist.
Symbol
RNF121
Positive Control 2
Cat. No. 17-012 - MCF7 Cell Slide
NCBI Official Name
Ring finger protein 121
NCBI Organism
Homo sapiens
Background Reference 01
Darom A, Bening-Abu-Shach U, and Broday L. RNF-121 is an endoplasmic reticulum-membrane E3 ubiquitin ligase involved in the regulation of B-integrin. Mol. Biol. Cell 2010; 21:1788-98.
Other Product Names
Ring finger protein 121
Tested Applications
ELISA, WB, ICC
Protein ID
21361732
Physical Properties
Liquid

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