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DEDD Antibody

CAT: 0223-59-960Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-59-960Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that contains a death effector domain (DED) . DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
9191
Swiss Prot
O75618
Accession Number
O75618
Host
Rabbit
Reactivity
Human
Immunogen
This DEDD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-191 amino acids from the Central region of human DEDD.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
37 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DEDD
NCBI Official Name
Death effector domain-containing protein
NCBI Organism
Homo sapiens
Background Reference 01
Thorenoor, N., et al. Biochemistry 49 (7) :1435-1447 (2010)
Background Reference 02
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Background Reference 03
Park, M.Y., et al. Int. J. Cancer 115 (3) :412-418 (2005)
Background Reference 04
Alcivar, A., et al. Oncogene 22 (2) :291-297 (2003)
Other Product Names
Death effector domain-containing protein, DEDPro1, Death effector domain-containing testicular molecule, FLDED-1, DEDD, DEDPRO1, DEFT
Tested Applications
WB
Physical Properties
Liquid

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