LRRC16A Antibody

• Background:

  LRRC16A binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity) .

• NCBI Gene ID:

  55604

• Swiss Prot:

  Q5VZK9

• Accession Number:

  Q5VZK9

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This LRRC16A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1152-1178 amino acids from the C-terminal region of human LRRC16A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  152 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  LRRC16A

• NCBI Official Name:

  Leucine-rich repeat-containing protein 16A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02:

  Polasek, O., et al. Croat. Med. J. 51 (1) :32-39 (2010)

• Background Reference 03:

  Gunjaca, G., et al. Croat. Med. J. 51 (1) :23-31 (2010)

• Background Reference 04:

  Van der Harst, P., et al. Hum. Mol. Genet. 19 (2) :387-395 (2010)

• Other Product Names:

  Leucine-rich repeat-containing protein 16A, CARMIL homolog, LRRC16A, CARMIL, CARMIL1a, LRRC16

• Tested Applications:

  WB

• Protein ID:

  74762279

• Physical Properties:

  Liquid