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UGT2B7 Antibody

CAT: 0223-59-716Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-716Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The UGTs (EC 2.4.1.17) serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B7 has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Its subcellular location is the microsome.
NCBI Gene ID
7364
Swiss Prot
P16662
Accession Number
P16662
Host
Rabbit
Reactivity
Human
Immunogen
This UGT2B7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-126 amino acids from the N-terminal region of human UGT2B7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
61 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
UGT2B7
NCBI Official Name
UDP-glucuronosyltransferase 2B7
NCBI Organism
Homo sapiens
Background Reference 01
Joy, M.S., et al. Eur. J. Clin. Pharmacol. 66 (11) :1119-1130 (2010)
Background Reference 02
Canzian, F., et al. Hum. Mol. Genet. 19 (19) :3873-3884 (2010)
Background Reference 03
Hu, M., et al. Pharmacogenet. Genomics 20 (10) :634-637 (2010)
Background Reference 04
Woillard, J.B., et al. BrClin Pharmacol 69 (6) :675-683 (2010)
Other Product Names
UDP-glucuronosyltransferase 2B7, UDPGT 2B7,4-catechol estrogen-specific UDPGT, UDP-glucuronosyltransferase 2B9, UDPGT 2B9, UDPGTh-2, UGT2B7, UGTB2B9
Tested Applications
WB
Protein ID
136727
Physical Properties
Liquid

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