UGT2B28 Antibody

• Background:

  UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme has glucuronidating capacity with steroid substrates such as 5-beta-androstane 3-alpha,17-beta-diol, estradiol, ADT, eugenol and bile acids. Only isoform 1 seems to be active.

• NCBI Gene ID:

  54490

• Swiss Prot:

  Q9BY64

• Accession Number:

  Q9BY64

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This UGT2B28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-246 amino acids from the Central region of human UGT2B28.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  61 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  UGT2B28

• NCBI Official Name:

  UDP-glucuronosyltransferase 2B28

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Setlur, S.R., et al. Cancer Epidemiol. Biomarkers Prev. 19 (1) :229-239 (2010)

• Background Reference 02:

  Ross, C.J., et al. Nat. Genet. 41 (12) :1345-1349 (2009)

• Background Reference 03:

  Menard, V., et al. Hum. Mutat. 30 (9) :1310-1319 (2009)

• Background Reference 04:

  Levesque, E., et al. Biochemistry 40 (13) :3869-3881 (2001)

• Other Product Names:

  UDP-glucuronosyltransferase 2B28, UDPGT 2B28, UGT2B28

• Tested Applications:

  WB

• Protein ID:

  20140759

• Physical Properties:

  Liquid