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UGT2B4 Antibody

CAT: 0223-60-694Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-694Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol) . It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
NCBI Gene ID
7363
Swiss Prot
P06133
Accession Number
P06133
Host
Rabbit
Reactivity
Human
Immunogen
This UGT2B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-96 amino acids from the N-terminal region of human UGT2B4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
61 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
UGT2B4
NCBI Official Name
UDP-glucuronosyltransferase 2B4
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Levesque, E., et al. Pharmacogenet. Genomics 20 (3) :195-210 (2010)
Background Reference 03
Yong, M., et al. Cancer Epidemiol. Biomarkers Prev. 19 (2) :537-546 (2010)
Background Reference 04
Li, J., et al. Breast Cancer Res. 12 (2), R19 (2010) :
Other Product Names
UDP-glucuronosyltransferase 2B4, UDPGT 2B4, HLUG25, Hyodeoxycholic acid-specific UDPGT, UDPGTh-1, UGT2B4, UGT2B11
Tested Applications
WB
Protein ID
6175083
Physical Properties
Liquid

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