UGT2B4 Antibody

• Background:

  UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol) . It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.

• NCBI Gene ID:

  7363

• Swiss Prot:

  P06133

• Accession Number:

  P06133

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This UGT2B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-96 amino acids from the N-terminal region of human UGT2B4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  61 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  UGT2B4

• NCBI Official Name:

  UDP-glucuronosyltransferase 2B4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02:

  Levesque, E., et al. Pharmacogenet. Genomics 20 (3) :195-210 (2010)

• Background Reference 03:

  Yong, M., et al. Cancer Epidemiol. Biomarkers Prev. 19 (2) :537-546 (2010)

• Background Reference 04:

  Li, J., et al. Breast Cancer Res. 12 (2), R19 (2010) :

• Other Product Names:

  UDP-glucuronosyltransferase 2B4, UDPGT 2B4, HLUG25, Hyodeoxycholic acid-specific UDPGT, UDPGTh-1, UGT2B4, UGT2B11

• Tested Applications:

  WB

• Protein ID:

  6175083

• Physical Properties:

  Liquid