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SELE Antibody

CAT: 0223-59-653Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-653Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
NCBI Gene ID
6401
Swiss Prot
P16581
Accession Number
P16581
Host
Rabbit
Reactivity
Human
Immunogen
This TRAIL antibody is generated from rabbits immunized with a recombinant protein from the human TRAIL.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
67 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SELE
NCBI Official Name
E-selectin
NCBI Organism
Homo sapiens
Background Reference 01
Palmer, C.N., et al. Diabetes 59 (11) :2945-2948 (2010)
Background Reference 02
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Background Reference 03
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 04
Wayman, A.M., et al. Biophys. J. 99 (4) :1166-1174 (2010)
Other Product Names
E-selectin, CD62 antigen-like family member E, Endothelial leukocyte adhesion molecule 1, ELAM-1, Leukocyte-endothelial cell adhesion molecule 2, LECAM2, CD62E, SELE, ELAM1
Tested Applications
WB
Protein ID
126180
Physical Properties
Liquid

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