SELP Antibody

• Background :

  This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.

• NCBI Gene ID :

  6403

• Swiss Prot :

  P16109

• Host :

  Rabbit

• Reactivity :

  Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 220-319 of human SELP (NP_002996.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Immunology, Stem Cell

• Purification :

  Affinity purification

• Positive Control :

  Mouse kidney

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 100kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  SELP

• Positive Control 2 :

  Rat brain

• NCBI Official Name :

  Selectin P (granule membrane protein 140kDa, antigen CD62)

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  SELP, CD62P, CD62, GMP-140, GMRP, Granule membrane protein 140, LECAM3, P-selectin, PSEL, CD62P antigen, GMP140, Granulocyte membrane protein, GRMP, PADGEM

• Tested Applications :

  WB

• Physical Properties :

  Liquid