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SELS Antibody

CAT: 0223-26-281Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-26-281Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SELS is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response.This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
55829
Swiss Prot
Q9BQE4
Accession Number
NP_060915
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SELS.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer, Signal Transduction, Immunology
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SELS antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
21 kDa
Applications Notes
SELS antibody can be used for detection of SELS by ELISA at 1:312500. SELS antibody can be used for detection of SELS by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
VIMP
NCBI Official Name
VCP-interacting membrane protein
NCBI Organism
Homo sapiens
Background Reference 01
Moses, E.K., Am. J. Obstet. Gynecol. 198 (3), 336 (2008) .
Other Product Names
SELS, AD-015, ADO15, MGC104346, MGC2553, SBBI8, SEPS1, VIMP, SELS
Tested Applications
ELISA, WB
Protein ID
33285002
Physical Properties
Liquid

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