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NEO1 Antibody

CAT: 0223-59-445Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-445Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq].
NCBI Gene ID
4756
Swiss Prot
Q92859
Accession Number
Q92859
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This NEO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 657-685 amino acids from the Central region of human NEO1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
160 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NEO1
NCBI Official Name
Neogenin
NCBI Organism
Homo sapiens
Background Reference 01
Bradford, D., et al. J. Comp. Neurol. 518 (16) :3237-3253 (2010)
Background Reference 02
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Background Reference 03
Zhang, A.S., et al. J. Biol. Chem. 284 (34) :22580-22589 (2009)
Background Reference 04
Fujita, Y., et al. Cell Death Differ. 15 (10) :1593-1608 (2008)
Other Product Names
Neogenin, Immunoglobulin superfamily DCC subclass member 2, NEO1, IGDCC2, NGN
Tested Applications
WB
Protein ID
116242676
Physical Properties
Liquid

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