TCN1 Antibody

• Background:

  This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells. [provided by RefSeq].

• NCBI Gene ID:

  6947

• Swiss Prot:

  P20061

• Accession Number:

  P20061

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TCN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 406-433 amino acids from the C-terminal region of human TCN1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  48 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  TCN1

• NCBI Official Name:

  Transcobalamin-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02:

  Garrod, M.G., et al. EurClin Nutr 64 (5) :503-509 (2010)

• Background Reference 03:

  Matteini, A.M., et al.Nutr Health Aging 14 (1) :73-77 (2010)

• Background Reference 04:

  McGeachie, M., et al. Circulation 120 (24) :2448-2454 (2009)

• Other Product Names:

  Transcobalamin-1, TC-1, Haptocorrin, HC, Protein R, Transcobalamin I, TC I, TCI, TCN1, TC1

• Tested Applications:

  WB

• Protein ID:

  146345530

• Physical Properties:

  Liquid