ZCCHC12 Antibody

• Background:

  Transcriptional coactivator in the bone morphogenetic protein (BMP) -signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression (By similarity) .

• NCBI Gene ID:

  170261

• Swiss Prot:

  Q6PEW1

• Accession Number:

  Q6PEW1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ZCCHC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the C-terminal region of human ZCCHC12.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  45 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ZCCHC12

• NCBI Official Name:

  Zinc finger CCHC domain-containing protein 12

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Cho, G., et al. J. Biol. Chem. 284 (29) :19592-19600 (2009)

• Background Reference 02:

  Li, H., et al. Acta Biochim. Biophys. Sin. (Shanghai) 41 (7) :535-544 (2009)

• Background Reference 03:

  Cho, G., et al. Am. J. Med. Genet.146A (20), 2644-2650 (2008) :

• Background Reference 04:

  Cho, G., et al. Mol. Cell. Biol. 28 (5) :1565-1572 (2008)

• Other Product Names:

  Zinc finger CCHC domain-containing protein 12, Smad-interacting zinc finger protein 1, ZCCHC12, SIZN1

• Tested Applications:

  WB

• Protein ID:

  85718626

• Physical Properties:

  Liquid