ZCCHC12 Antibody

• Background:

  ZCCHC12 contains 1 CCHC-type zinc finger. ZCCHC12 is the transcriptional coactivator in the bone morphogenetic protein (BMP) -signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression.

• NCBI Gene ID:

  170261

• Swiss Prot:

  Q6PEW1

• Accession Number:

  NP_776159

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZCCHC12.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ZCCHC12 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  45 kDa

• Applications Notes:

  ZCCHC12 antibody can be used for detection of ZCCHC12 by ELISA at 1:1562500. ZCCHC12 antibody can be used for detection of ZCCHC12 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  ZCCHC12

• NCBI Official Name:

  Zinc finger, CCHC domain containing 12

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Cho, G., (2008) Mol. Cell. Biol. 28 (5), 1565-1572.

• Other Product Names:

  ZCCHC12, FLJ16123, SIZN, SIZN1, PNMA7A

• Tested Applications:

  ELISA, WB

• Protein ID:

  28557790

• Physical Properties:

  Liquid