TTDN1 Antibody

• Background:

  The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy.

• NCBI Gene ID:

  136647

• Swiss Prot:

  Q8TAP9

• Accession Number:

  Q8TAP9

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TTDN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-177 amino acids from the C-terminal region of human TTDN1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  19 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  MPLKIP

• NCBI Official Name:

  M-phase-specific PLK1-interacting protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Zhang, Y., et al. Cell. Mol. Life Sci. 64 (5) :632-640 (2007)

• Background Reference 02:

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Background Reference 03:

  Botta, E., et al. Hum. Mutat. 28 (1) :92-96 (2007)

• Background Reference 04:

  Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

• Other Product Names:

  M-phase-specific PLK1-interacting protein, TTD non-photosensitive 1 protein, MPLKIP, C7orf11, TTDN1

• Tested Applications:

  WB

• Protein ID:

  71153365

• Physical Properties:

  Liquid