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PPIE Antibody

CAT: 0223-59-279Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-279Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified.
NCBI Gene ID
10450
Swiss Prot
Q9UNP9
Accession Number
Q9UNP9
Host
Rabbit
Reactivity
Human
Immunogen
This PPIE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-49 amino acids from the N-terminal region of human PPIE.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PPIE
NCBI Official Name
Peptidyl-prolyl cis-trans isomerase E
NCBI Organism
Homo sapiens
Background Reference 01
Park, S., et al. Biochemistry 49 (31) :6576-6586 (2010)
Background Reference 02
Hom, R.A., et al. J. Mol. Biol. 400 (2) :145-154 (2010)
Background Reference 03
Wang, Z., et al. Cell 141 (7) :1183-1194 (2010)
Background Reference 04
Naukkarinen, J., et al. PLoS Genet. (6), E1000976 (2010) :
Other Product Names
Peptidyl-prolyl cis-trans isomerase E, PPIase E, Cyclophilin E, Cyclophilin-33, Rotamase E, PPIE, CYP33
Tested Applications
WB
Protein ID
13124097
Physical Properties
Liquid

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