PPIF Antibody

• Background:

  PPIF is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.

• NCBI Gene ID:

  10105

• Swiss Prot:

  P30405

• Accession Number:

  NP_005720

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PPIF.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Tranfected 293T Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PPIF antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  19 kDa

• Applications Notes:

  PPIF antibody can be used for detection of PPIF by ELISA at 1:62500. PPIF antibody can be used for detection of PPIF by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  PPIF

• NCBI Official Name:

  Peptidylprolyl isomerase F

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Clark, H.F., (2003) Genome Res. 13 (10), 2265-2270.

• Other Product Names:

  PPIF, CYP3, Cyp-D, FLJ90798, MGC117207, CypD, CyP-M

• Tested Applications:

  ELISA, WB

• Protein ID:

  5031987

• Physical Properties:

  Liquid