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PPIB Antibody

CAT: 0223-29-987Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-29-987Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PPIB is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression.
NCBI Gene ID
5479
Swiss Prot
A8K534
Accession Number
NP_000933
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PPIB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PPIB antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
24 kDa
Applications Notes
PPIB antibody can be used for detection of PPIB by ELISA at 1:312500. PPIB antibody can be used for detection of PPIB by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
PPIB
NCBI Official Name
Peptidylprolyl isomerase B (cyclophilin B)
NCBI Organism
Homo sapiens
Background Reference 01
Watashi, K., (2005) Mol. Cell 19 (1), 111-122.
Other Product Names
PPIB, CYP-S1, CYPB, MGC14109, MGC2224, SCYLP, OI9, HEL-S-39
Tested Applications
ELISA, WB, IHC
Protein ID
4758950
Physical Properties
Liquid

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