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TPM2 Antibody

CAT: 0223-59-276Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-276Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
7169
Swiss Prot
P07951
Accession Number
P07951
Host
Rabbit
Reactivity
Human
Immunogen
This TPM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-280 amino acids from the C-terminal region of human TPM2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Rabbit, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TPM2
NCBI Official Name
Tropomyosin beta chain
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Martins-de-Souza, D., et al.Psychiatr Res 44 (14) :989-991 (2010)
Background Reference 03
Assinder, S.J., et al. Mol. Carcinog. 49 (6) :525-531 (2010)
Background Reference 04
Ochala, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (21) :9807-9812 (2010)
Other Product Names
Tropomyosin beta chain, Beta-tropomyosin, Tropomyosin-2, TPM2, TMSB
Tested Applications
WB
Protein ID
136090
Physical Properties
Liquid

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