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TPM4 Antibody

CAT: 0223-56-627Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-627Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
NCBI Gene ID
7171
Swiss Prot
P67936
Accession Number
P67936
Host
Rabbit
Reactivity
Human
Immunogen
This TPM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human TPM4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Pig
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
29 kDa
Fragment
Rabbit Ig
Symbol
TPM4
NCBI Official Name
Tropomyosin alpha-4 chain
NCBI Organism
Homo sapiens
Background Reference 01
Martins-de-Souza, D., et al.Psychiatr Res 44 (14) :989-991 (2010)
Background Reference 02
Vlahovich, N., et al. Cell Motil. Cytoskeleton 65 (1) :73-85 (2008)
Background Reference 03
Montesano Gesualdi, N., et al. Free Radic. Res. 40 (5) :467-476 (2006)
Background Reference 04
Hossain, M.M., et al. J. Biol. Chem. 280 (51) :42442-42453 (2005)
Other Product Names
Tropomyosin alpha-4 chain, TM30p1, Tropomyosin-4, TPM4
Tested Applications
WB, Flow
Protein ID
54039751
Physical Properties
Liquid

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