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LETM1 Antibody

CAT: 0223-59-207Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-207Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19.
NCBI Gene ID
3954
Swiss Prot
O95202
Accession Number
O95202
Host
Rabbit
Reactivity
Human
Immunogen
This LETM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 577-607 amino acids from the C-terminal region of human LETM1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
83 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
LETM1
NCBI Official Name
LETM1 and EF-hand domain-containing protein 1, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Jiang, D., et al. Science 326 (5949) :144-147 (2009)
Background Reference 02
Piao, L., et al. Cell. Signal. 21 (5) :767-777 (2009)
Background Reference 03
Piao, L., et al. Cancer Res. 69 (8) :3397-3404 (2009)
Background Reference 04
Tamai, S., et al. J. Cell. Sci. 121 (PT 15), 2588-2600 (2008) :
Other Product Names
LETM1 and EF-hand domain-containing protein 1, mitochondrial, Leucine zipper-EF-hand-containing transmembrane protein 1, LETM1
Tested Applications
WB
Physical Properties
Liquid

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