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PRIM2 Antibody

CAT: 0223-59-198Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-198Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the large, 58 kDa primase subunit. [provided by RefSeq].
NCBI Gene ID
5558
Swiss Prot
P49643
Accession Number
P49643
Host
Rabbit
Reactivity
Human
Immunogen
This PRIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-345 amino acids from the Central region of human PRIM2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
59 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PRIM2
NCBI Official Name
DNA primase large subunit
NCBI Organism
Homo sapiens
Background Reference 01
Vaithiyalingam, S., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (31) :13684-13689 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Weiner, B.E., et al. J. Biol. Chem. 282 (46) :33444-33451 (2007)
Background Reference 04
Rush, J., et al. Nat. Biotechnol. 23 (1) :94-101 (2005)
Other Product Names
DNA primase large subunit, 277-, DNA primase 58 kDa subunit, p58, PRIM2, PRIM2A
Tested Applications
WB
Protein ID
51338777
Physical Properties
Liquid

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