AP2S1 Antibody

• Background:

  One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing has been observed in this gene and results in two known transcripts.

• NCBI Gene ID:

  1175

• Swiss Prot:

  P53680

• Accession Number:

  P53680

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This AP2S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the Central region of human AP2S1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  17 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  AP2S1

• NCBI Official Name:

  AP-2 complex subunit sigma

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Stove, V., et al. J. Virol. 79 (17) :11422-11433 (2005)

• Background Reference 02:

  Lu, W., et al. Neuron 47 (3) :407-421 (2005)

• Background Reference 03:

  Collins, B.M., et al. Cell 109 (4) :523-535 (2002)

• Background Reference 04:

  Yano, H., et al. J. Neurosci. 21 (3), RC125 (2001) :

• Other Product Names:

  AP-2 complex subunit sigma, Adaptor protein complex AP-2 subunit sigma, Adaptor-related protein complex 2 subunit sigma, Clathrin assembly protein 2 sigma small chain, Clathrin coat assembly protein AP17, Clathrin coat-associated protein AP17, HA2 17 kDa subunit, Plasma membrane adaptor AP-2 17 kDa protein, Sigma2-adaptin, AP2S1, AP17, CLAPS2

• Tested Applications:

  WB

• Protein ID:

  51338780

• Physical Properties:

  Liquid