AP2B1 Antibody

• Background :

  The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  163

• Swiss Prot :

  P63010

• Accession Number :

  P63010

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This AP2B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 517-546 amino acids from the Central region of human AP2B1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  105 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  AP2B1

• NCBI Official Name :

  AP-2 complex subunit beta

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Kahlfeldt, N., et al. J. Biol. Chem. 285 (4) :2734-2749 (2010)

• Background Reference 02 :

  Hood, F.E., et al. J. Cell. Sci. 122 (PT 13), 2185-2190 (2009) :

• Background Reference 03 :

  Grass, B., et al. Histopathology 54 (7) :873-879 (2009)

• Background Reference 04 :

  Keyel, P.A., et al. Mol. Biol. Cell 19 (12) :5309-5326 (2008)

• Other Product Names :

  AP-2 complex subunit beta, AP105B, Adaptor protein complex AP-2 subunit beta, Adaptor-related protein complex 2 subunit beta, Beta-2-adaptin, Beta-adaptin, Clathrin assembly protein complex 2 beta large chain, Plasma membrane adaptor HA2/AP2 adaptin beta subunit, AP2B1, ADTB2, CLAPB1

• Tested Applications :

  WB

• Protein ID :

  51702211

• Physical Properties :

  Liquid