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RRN3 Antibody

CAT: 0223-59-102Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-102Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC) . Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction (By similarity) .
NCBI Gene ID
54700
Swiss Prot
Q9NYV6
Accession Number
Q9NYV6
Host
Rabbit
Reactivity
Human
Immunogen
This RRN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-305 amino acids from the Central region of human RRN3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
74 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RRN3
NCBI Official Name
RNA polymerase I-specific transcription initiation factor RRN3
NCBI Organism
Homo sapiens
Background Reference 01
Bierhoff, H., et al. Mol. Cell. Biol. 28 (16) :4988-4998 (2008)
Background Reference 02
Amit, M., et al. BMC Mol. Biol. 8, 109 (2007) :
Background Reference 03
Mayer, C., et al. Genes Dev. 18 (4) :423-434 (2004)
Background Reference 04
Hirschler-Laszkiewicz, I., et al. J. Biol. Chem. 278 (21) :18953-18959 (2003)
Other Product Names
RNA polymerase I-specific transcription initiation factor RRN3, Transcription initiation factor IA, TIF-IA, RRN3, TIFIA
Tested Applications
WB
Protein ID
74719591
Physical Properties
Liquid

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