PPME1 Antibody

• Background:

  Protein phosphatase methylesterase-1 catalyzes the demethylation of the protein phosphatase-2A catalytic subunit (PPP2CA; MIM 176915) (Ogris et al., 1999 [PubMed 10318862]) .

• NCBI Gene ID:

  51400

• Swiss Prot:

  Q9Y570

• Accession Number:

  Q9Y570

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PPME1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 351-379 amino acids from the C-terminal region of human PPME1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  42 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PPME1

• NCBI Official Name:

  Protein phosphatase methylesterase 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Puustinen, P., et al. Cancer Res. 69 (7) :2870-2877 (2009)

• Background Reference 02:

  Longin, S., et al. Exp. Cell Res. 314 (1) :68-81 (2008)

• Background Reference 03:

  Gevaert, K., et al. Nat. Biotechnol. 21 (5) :566-569 (2003)

• Background Reference 04:

  Ogris, E., et al. J. Biol. Chem. 274 (20) :14382-14391 (1999)

• Other Product Names:

  Protein phosphatase methylesterase 1, PME-1, PPME1, PME1

• Tested Applications:

  WB

• Protein ID:

  47606055

• Physical Properties:

  Liquid