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AP4B1 Antibody

CAT: 0223-59-083Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-083Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The heterotetrameric adaptor protein (AP) complexes sort integral membrane proteins at various stages of the endocytic and secretory pathways. AP4 is composed of 2 large chains, beta-4 (AP4B1) and epsilon-4 (AP4E1; MIM 607244), a medium chain, mu-4 (AP4M1; MIM 602296), and a small chain, sigma-4 (AP4S1; MIM 607243) .
NCBI Gene ID
10717
Swiss Prot
Q9Y6B7
Accession Number
Q9Y6B7
Host
Rabbit
Reactivity
Human
Immunogen
This AP4B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 492-520 amino acids from the Central region of human AP4B1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
83 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
AP4B1
NCBI Official Name
AP-4 complex subunit beta-1
NCBI Organism
Homo sapiens
Background Reference 01
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Background Reference 02
Cayrol, C., et al. Biochem. Biophys. Res. Commun. 298 (5) :720-730 (2002)
Background Reference 03
Takatsu, H., et al. Biochem. Biophys. Res. Commun. 284 (4) :1083-1089 (2001)
Background Reference 04
Hirst, J., et al. Mol. Biol. Cell 10 (8) :2787-2802 (1999)
Other Product Names
AP-4 complex subunit beta-1, AP-4 adaptor complex subunit beta, Adaptor-related protein complex 4 subunit beta-1, Beta subunit of AP-4, Beta4-adaptin, AP4B1
Tested Applications
WB
Protein ID
126302520
Physical Properties
Liquid