REXO2 Antibody

• Background:

  Nucleases are components of DNA and RNA metabolism that carry out functions in DNA repair, replication, and recombination and in RNA processing and degradation. SFN is a homolog of Orn, a 3-prime-to-5-prime exoribonuclease of E. coli that attacks the free 3-prime hydroxyl group on single-stranded RNA, releasing 5-prime mononucleotides in a sequential manner.

• NCBI Gene ID:

  25996

• Swiss Prot:

  Q9Y3B8

• Accession Number:

  Q9Y3B8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This REXO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 129-157 amino acids from the Central region of human REXO2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  27 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  REXO2

• NCBI Official Name:

  Oligoribonuclease, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Young Park, A., et al. Protein Expr. Purif. 57 (2) :180-187 (2008)

• Background Reference 02:

  Rush, J., et al. Nat. Biotechnol. 23 (1) :94-101 (2005)

• Background Reference 03:

  Ito, S., et al. Photochem. Photobiol. 80 (2) :281-285 (2004)

• Background Reference 04:

  Simpson, J.C., et al. EMBO Rep. 1 (3) :287-292 (2000)

• Other Product Names:

  Oligoribonuclease, mitochondrial, 31--, RNA exonuclease 2 homolog, Small fragment nuclease, REXO2, SFN, SMFN

• Tested Applications:

  WB

• Protein ID:

  116242694

• Physical Properties:

  Liquid