ALG2 Antibody

• Background:

  This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man (2) GlcNAc (2) -dolichol diphosphate and Man (1) GlcNAc (2) -dolichol diphosphate to form Man (3) GlcNAc (2) -dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii) . Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  85365

• Swiss Prot:

  Q9H553

• Accession Number:

  Q9H553

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ALG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-282 amino acids from the Central region of human ALG2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  47 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ALG2

• NCBI Official Name:

  Alpha-1,3/1,6-mannosyltransferase ALG2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Inuzuka, T., et al. BMC Struct. Biol. 10, 25 (2010) :

• Background Reference 02:

  Okumura, M., et al. Biochem. Biophys. Res. Commun. 386 (1) :237-241 (2009)

• Background Reference 03:

  Hoj, B.R., et al. Biochem. Biophys. Res. Commun. 378 (1) :145-148 (2009)

• Background Reference 04:

  Mahul-Mellier, A.L., et al. J. Biol. Chem. 283 (50) :34954-34965 (2008)

• Other Product Names:

  Alpha-1,3/1,6-mannosyltransferase ALG2, Asparagine-linked glycosylation protein 2 homolog, GDP-Man:Man (1) GlcNAc (2) -PP-Dol alpha-1,3-mannosyltransferase, GDP-Man:Man (1) GlcNAc (2) -PP-dolichol mannosyltransferase, GDP-Man:Man (2) GlcNAc (2) -PP-Dol alpha-1,6-mannosyltransferase, ALG2

• Tested Applications:

  WB

• Protein ID:

  46395991

• Physical Properties:

  Liquid