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ALG2 Antibody

CAT: 0223-59-049Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-59-049Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man (2) GlcNAc (2) -dolichol diphosphate and Man (1) GlcNAc (2) -dolichol diphosphate to form Man (3) GlcNAc (2) -dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii) . Alternative splicing results in multiple transcript variants.
NCBI Gene ID
85365
Swiss Prot
Q9H553
Accession Number
Q9H553
Host
Rabbit
Reactivity
Human
Immunogen
This ALG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-282 amino acids from the Central region of human ALG2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ALG2
NCBI Official Name
Alpha-1,3/1,6-mannosyltransferase ALG2
NCBI Organism
Homo sapiens
Background Reference 01
Inuzuka, T., et al. BMC Struct. Biol. 10, 25 (2010) :
Background Reference 02
Okumura, M., et al. Biochem. Biophys. Res. Commun. 386 (1) :237-241 (2009)
Background Reference 03
Hoj, B.R., et al. Biochem. Biophys. Res. Commun. 378 (1) :145-148 (2009)
Background Reference 04
Mahul-Mellier, A.L., et al. J. Biol. Chem. 283 (50) :34954-34965 (2008)
Other Product Names
Alpha-1,3/1,6-mannosyltransferase ALG2, Asparagine-linked glycosylation protein 2 homolog, GDP-Man:Man (1) GlcNAc (2) -PP-Dol alpha-1,3-mannosyltransferase, GDP-Man:Man (1) GlcNAc (2) -PP-dolichol mannosyltransferase, GDP-Man:Man (2) GlcNAc (2) -PP-Dol alpha-1,6-mannosyltransferase, ALG2
Tested Applications
WB
Protein ID
46395991
Physical Properties
Liquid

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