POLR2D Antibody

CAT: 0223-59-030Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-59-030Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the fourth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit is associated with the polymerase under suboptimal growth conditions and may have a stress protective role. A sequence for a ribosomal pseudogene is contained within the 3' untranslated region of the transcript from this gene.
NCBI Gene ID
5433
Swiss Prot
O15514
Accession Number
O15514
Host
Rabbit
Reactivity
Human
Immunogen
This POLR2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the Central region of human POLR2D.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
16 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
POLR2D
NCBI Official Name
DNA-directed RNA polymerase II subunit RPB4
NCBI Organism
Homo sapiens
Background Reference 01
Michiels, S., et al. Carcinogenesis 30 (5) :763-768 (2009)
Background Reference 02
Meka, H., et al. Nucleic Acids Res. 33 (19) :6435-6444 (2005)
Background Reference 03
Zhou, M., et al. Proc. Natl. Acad. Sci. U.S.A. 100 (22) :12666-12671 (2003)
Background Reference 04
Kaehlcke, K., et al. Mol. Cell 12 (1) :167-176 (2003)
Other Product Names
DNA-directed RNA polymerase II subunit RPB4, RNA polymerase II subunit B4, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16 kDa subunit, RPB16, POLR2D
Tested Applications
WB
Physical Properties
Liquid

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