POLR2G Antibody

• Background:

  This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation.

• NCBI Gene ID:

  5436

• Swiss Prot:

  P62487

• Accession Number:

  P62487

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This POLR2G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-154 amino acids from the C-terminal region of human POLR2G.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Zebrafish, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  19 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  POLR2G

• NCBI Official Name:

  DNA-directed RNA polymerase II subunit RPB7

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Cojocaru, M., et al. Biochem. J. 409 (1) :139-147 (2008)

• Background Reference 02:

  Ujvari, A., et al. Nat. Struct. Mol. Biol. 13 (1) :49-54 (2006)

• Background Reference 03:

  Meka, H., et al. Nucleic Acids Res. 33 (19) :6435-6444 (2005)

• Background Reference 04:

  Lehner, B., et al. Genomics 83 (1) :153-167 (2004)

• Other Product Names:

  DNA-directed RNA polymerase II subunit RPB7, RNA polymerase II subunit B7, DNA-directed RNA polymerase II subunit G, RNA polymerase II 19 kDa subunit, RPB19, POLR2G, RPB7

• Tested Applications:

  WB

• Protein ID:

  50403601

• Physical Properties:

  Liquid