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POLR2B Antibody

CAT: 0223-57-949Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-949Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA. [provided by RefSeq].
NCBI Gene ID
5431
Swiss Prot
P30876
Accession Number
P30876
Host
Rabbit
Reactivity
Human
Immunogen
This POLR2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 797-826 amino acids from the Central region of human POLR2B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
134 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
POLR2B
NCBI Official Name
DNA-directed RNA polymerase II subunit RPB2
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Michiels, S., et al. Carcinogenesis 30 (5) :763-768 (2009)
Background Reference 03
Tu, S., et al. Nat. Struct. Mol. Biol. 15 (4) :419-421 (2008)
Background Reference 04
Lee, J.H., et al. Mol. Cell. Biol. 28 (2) :609-618 (2008)
Other Product Names
DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2, POLR2B
Tested Applications
WB
Protein ID
401012
Physical Properties
Liquid

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