POLR2B Antibody

• Background:

  This gene encodes the second largest subunit of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into precursors of mRNA, snRNA and microRNA. This subunit and the largest subunit form opposite sides of the center cleft of Pol II. Deletion of the flap loop region of this subunit results in a decrease in the rate of transcriptional elongation. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  5431

• Swiss Prot:

  P30876

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human POLR2B (NP_000929.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  Affinity purification

• Positive Control:

  SH-SY5Y

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 134kDa

• Fragment:

  IgG

• Symbol:

  POLR2B

• Positive Control 2:

  A375

• Positive Control 3:

  HepG2

• Positive Control 4:

  BT-474

• Positive Control 5:

  Mouse brain

• Positive Control 6:

  Mouse spleen

• NCBI Official Name:

  Polymerase (RNA) II (DNA directed) polypeptide B, 140kDa

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  POLR2B, RPB2, POL2RB, hsRPB2, hRPB140

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid