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TBX4 Antibody

CAT: 0223-60-268Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-268Size:400 µL
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Background
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human homolog of mouse Tbx4, which is closely linked to Tbx2 on mouse chromosome 11. Similarly this gene, like TBX2, maps to human chromosome 17. Expression studies in mouse and chicken show that Tbx4 is expressed in developing hindlimb, but not in forelimb buds, suggesting a role for this gene in regulating limb development and specification of limb identity.
NCBI Gene ID
9496
Swiss Prot
P57082
Accession Number
P57082
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This TBX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-129 amino acids from the N-terminal region of human TBX4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Chicken, Rat, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TBX4
NCBI Official Name
T-box transcription factor TBX4
NCBI Organism
Homo sapiens
Background Reference 01
Kim, J.J., et al. J. Hum. Genet. 55 (1) :27-31 (2010)
Background Reference 02
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Background Reference 03
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Background Reference 04
Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)
Other Product Names
T-box transcription factor TBX4, T-box protein 4, TBX4
Tested Applications
WB
Protein ID
51338786
Physical Properties
Liquid

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