Products for Research Use Only

ARAP2 Antibody

CAT: 0223-58-826Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-58-826Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5) -trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics.
NCBI Gene ID
116984
Swiss Prot
Q8WZ64
Accession Number
Q8WZ64
Host
Rabbit
Reactivity
Human
Immunogen
This ARAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-93 amino acids from the N-terminal region of human ARAP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
193 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ARAP2
NCBI Official Name
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Gavicherla, B., et al. Infect. Immun. 78 (11) :4532-4541 (2010)
Background Reference 02
Liu, C., et al. Mol. Med. 14 (9-10), 575-581 (2008) :
Background Reference 03
Yoon, H.Y., et al. J. Cell. Sci. 119 (PT 22), 4650-4666 (2006) :
Background Reference 04
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Other Product Names
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2, Centaurin-delta-1, Cnt-d1, Protein PARX, ARAP2, CENTD1, KIAA0580
Tested Applications
WB
Protein ID
308153629
Physical Properties
Liquid