ARAP1 Antibody

• Background:

  The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3) -dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  116985

• Swiss Prot:

  Q96P48

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 834-1133 of human ARAP1 (NP_001128662.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 190kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  ARAP1

• Positive Control 2:

  LO2

• Positive Control 3:

  HeLa

• Positive Control 4:

  Mouse liver

• Positive Control 5:

  Rat liver

• NCBI Official Name:

  ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CENTD2, centaurin, delta 2, ARAP1, KIAA0782, ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1, CENTD2

• Tested Applications:

  WB

• Physical Properties:

  Liquid