PBXIP1 Antibody

• Background:

  Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.

• NCBI Gene ID:

  57326

• Swiss Prot:

  Q96AQ6

• Accession Number:

  Q96AQ6

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PBXIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 472-501 amino acids from the C-terminal region of human PBXIP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  81 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PBXIP1

• NCBI Official Name:

  Pre-B-cell leukemia transcription factor-interacting protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)

• Background Reference 02:

  Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

• Background Reference 03:

  Lim, J., et al. Cell 125 (4) :801-814 (2006)

• Background Reference 04:

  Abramovich, C., et al. Oncogene 21 (44) :6766-6771 (2002)

• Other Product Names:

  Pre-B-cell leukemia transcription factor-interacting protein 1, Hematopoietic PBX-interacting protein, PBXIP1, HPIP

• Tested Applications:

  WB

• Protein ID:

  74751749

• Physical Properties:

  Liquid