PBXIP1 Antibody

• Background:

  PBXIP1 is the regulator of pre-B-cell leukemia transcription factors (BPXs) function. It inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. PBXIP1 tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.

• NCBI Gene ID:

  57326

• Swiss Prot:

  Q96AQ6

• Accession Number:

  NP_065385

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PBXIP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Tranfected 293T Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PBXIP1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  81 kDa

• Applications Notes:

  PBXIP1 antibody can be used for detection of PBXIP1 by ELISA at 1:62500. PBXIP1 antibody can be used for detection of PBXIP1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  PBXIP1

• NCBI Official Name:

  Pre-B-cell leukemia homeobox interacting protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lim, J., (2006) Cell 125 (4), 801-814.

• Other Product Names:

  PBXIP1, HPIP

• Tested Applications:

  ELISA, WB

• Protein ID:

  19923830

• Physical Properties:

  Liquid