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TTC8 Antibody

CAT: 0223-58-745Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-745Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized.
NCBI Gene ID
123016
Swiss Prot
Q8TAM2
Accession Number
Q8TAM2
Host
Rabbit
Reactivity
Human
Immunogen
This TTC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human TTC8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
62 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TTC8
NCBI Official Name
Tetratricopeptide repeat protein 8
NCBI Organism
Homo sapiens
Background Reference 01
Riazuddin, S.A., et al. Am. J. Hum. Genet. 86 (5) :805-812 (2010)
Background Reference 02
Bin, J., et al. Hum. Mutat. 30 (7), E737-E746 (2009) :
Background Reference 03
Chung, W.K., et al. Hum. Hered. 67 (3) :193-205 (2009)
Background Reference 04
Nachury, M.V., et al. Cell 129 (6) :1201-1213 (2007)
Other Product Names
Tetratricopeptide repeat protein 8, TPR repeat protein 8, Bardet-Biedl syndrome 8 protein, TTC8, BBS8
Tested Applications
WB
Protein ID
308153511
Physical Properties
Liquid

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