TTC5 Antibody

• Background:

  TTC5 is an adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. It is required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. It prevents p53/TP53 degradation by MDM2.

• NCBI Gene ID:

  91875

• Swiss Prot:

  Q8N0Z6

• Accession Number:

  NP_612385

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TTC5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TTC5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  49 kDa

• Applications Notes:

  TTC5 antibody can be used for detection of TTC5 by ELISA at 1:312500. TTC5 antibody can be used for detection of TTC5 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  TTC5

• NCBI Official Name:

  Tetratricopeptide repeat domain 5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Demonacos, C., (2001) Mol. Cell 8 (1), 71-84.

• Other Product Names:

  TTC5, Strap

• Tested Applications:

  ELISA, WB

• Protein ID:

  226498382

• Physical Properties:

  Liquid